Welcome Reception and Poster Session 1
Sunday, January 11, 2015: 7:30 PM-9:30 PM
California Ballroom C and Santa Fe Room
Self-resistance mechanisms of actinomycetes producing lipid II-targeting antibiotics
Evi Stegmann1, Regina Kiliian2, Hans-Joerg Frasch3, Roberta Pozzi4 and Wolfgang Wohlleben1, (1)Microbiology/Biotechnology, University Tuebingen, Tuebingen, (2)Microbiology/biotechnology, University of Tuebingen, (3)University of Tuebingen, (4)Microbiology/Biotechnology, University of Tuebingen
Evi Stegmann1, Regina Kiliian2, Hans-Joerg Frasch3, Roberta Pozzi4 and Wolfgang Wohlleben1, (1)Microbiology/Biotechnology, University Tuebingen, Tuebingen, (2)Microbiology/biotechnology, University of Tuebingen, (3)University of Tuebingen, (4)Microbiology/Biotechnology, University of Tuebingen
Chemical space exploration: targeting the undiscovered
Dimitrios J. Floros1, Dr. Nobuhiro Koyama2, Paul R. Jensen3 and Pieter C. Dorrestein2, (1)Chemistry and Biochemistry, UC San Diego, La Jolla, CA, (2)Skaggs School of Pharmacy & Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, (3)Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, La Jolla, CA
Dimitrios J. Floros1, Dr. Nobuhiro Koyama2, Paul R. Jensen3 and Pieter C. Dorrestein2, (1)Chemistry and Biochemistry, UC San Diego, La Jolla, CA, (2)Skaggs School of Pharmacy & Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, (3)Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, La Jolla, CA
New natural products, mangromicins, from Lechevalieria aerocolonigenes K10-0216
Dr. Takuji Nakashima1, Prof. Yoko Takahashi2 and Prof. Satoshi Omura1, (1)Kitasato Institute for Life Sciences, Kitasato University, Tokyo, (2)Kitasato University, Tokyo
Dr. Takuji Nakashima1, Prof. Yoko Takahashi2 and Prof. Satoshi Omura1, (1)Kitasato Institute for Life Sciences, Kitasato University, Tokyo, (2)Kitasato University, Tokyo
Pseudomonas metabolic diversity captured by GNPS molecular networking
Don D. Nguyen1, Alexey Melnik2, Dr. Nobuhiro Koyama2, Jinshu Fang1 and Pieter C. Dorrestein2, (1)Chemistry & Biochemistry, University of California San Diego, La Jolla, CA, (2)Skaggs School of Pharmacy & Pharmaceutical Sciences, University of California San Diego, La Jolla, CA
Don D. Nguyen1, Alexey Melnik2, Dr. Nobuhiro Koyama2, Jinshu Fang1 and Pieter C. Dorrestein2, (1)Chemistry & Biochemistry, University of California San Diego, La Jolla, CA, (2)Skaggs School of Pharmacy & Pharmaceutical Sciences, University of California San Diego, La Jolla, CA
Biological activity of citridone A and its derivatives
Dr. Takashi Fukuda1, Mr. Kenta Shimoyama2, Prof. Tohru Nagamitsu1 and Prof. Hiroshi Tomoda1, (1)Graduate School of Pharmaceutical Sciences, Kitasato University, Tokyo, (2)Graduate School of Pharmaceutical Sciences, Kitasato University
Dr. Takashi Fukuda1, Mr. Kenta Shimoyama2, Prof. Tohru Nagamitsu1 and Prof. Hiroshi Tomoda1, (1)Graduate School of Pharmaceutical Sciences, Kitasato University, Tokyo, (2)Graduate School of Pharmaceutical Sciences, Kitasato University
Natural low molecular mass organic compound with oxidase activity
Mr. Tatsuya Nishiyama1, Dr. Yoshiteru Hashimoto1, Dr. Hitoshi Kusakabe2, Dr. Takuto Kumano1 and Prof. Michihiko Kobayashi1, (1)Institute of Applied Biochemistry, and Graduate School of Life and Environmental Sciences, University of Tsukuba, Tsukuba, (2)Enzyme-Sensor Co., Ltd., Tsukuba
Mr. Tatsuya Nishiyama1, Dr. Yoshiteru Hashimoto1, Dr. Hitoshi Kusakabe2, Dr. Takuto Kumano1 and Prof. Michihiko Kobayashi1, (1)Institute of Applied Biochemistry, and Graduate School of Life and Environmental Sciences, University of Tsukuba, Tsukuba, (2)Enzyme-Sensor Co., Ltd., Tsukuba
Antibacterial tricyclic peptides inhibiting fatty acid synthesis from Streptomyces sp.
Won-Gon Kim, Superbacteria Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Kores
Won-Gon Kim, Superbacteria Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Kores
Construction of a microbial metabolite fraction library with NPPlot for discovery of novel metabolites
Dr. Toshihiko Nogawa1, Ms. Akiko Okano2, Mr. Chung Liang Lim3, Shunji Takahashi4 and Hiroyuki Osada4, (1)RIKEN CSRS, Wako Saitama, Japan, (2)RIKEN CSRS, Wako, Saitama, Japan, (3)Antibiotics Laboratory, RIKEN, Wako, Saitama, Japan, (4)RIKEN Center for Sustainable Resource Science, Wako-shi, Saitama
Dr. Toshihiko Nogawa1, Ms. Akiko Okano2, Mr. Chung Liang Lim3, Shunji Takahashi4 and Hiroyuki Osada4, (1)RIKEN CSRS, Wako Saitama, Japan, (2)RIKEN CSRS, Wako, Saitama, Japan, (3)Antibiotics Laboratory, RIKEN, Wako, Saitama, Japan, (4)RIKEN Center for Sustainable Resource Science, Wako-shi, Saitama
Cysteine biosynthesis inhibitors of Entamoeba histolytica from secondary metabolites of microorganisms
Prof. Kazuro Shiomi1, Dr. Mihoko Mori1, Mr. Kazunari Sakai2, Mr. Satoshi Tsuge2, Dr. Kenichi Nonaka1, Dr. Atsuko Matsumoto1, Prof. Satoshi Omura1 and Prof. Tomoyoshi Nozaki3, (1)Kitasato Institute for Life Sciences, Kitasato University, Tokyo, (2)Graduate School of Infection Control Sciences, Kitasato University, Tokyo, (3)Department of Parasitology, National Institute of Infectious Diseases, Tokyo
Prof. Kazuro Shiomi1, Dr. Mihoko Mori1, Mr. Kazunari Sakai2, Mr. Satoshi Tsuge2, Dr. Kenichi Nonaka1, Dr. Atsuko Matsumoto1, Prof. Satoshi Omura1 and Prof. Tomoyoshi Nozaki3, (1)Kitasato Institute for Life Sciences, Kitasato University, Tokyo, (2)Graduate School of Infection Control Sciences, Kitasato University, Tokyo, (3)Department of Parasitology, National Institute of Infectious Diseases, Tokyo
Decontamination of Escherichia coli O157:H7 from the surface of leafy greens using copper and ascorbic acid alone or in combination with organic acids
Salam Ibrahim, Food and Nutritional Sciences, North Carolina A & T State University, Greensboro, NC, Sulaiman Aljaloud, Department of Exercise Physiology, King Saud University,, Riyadh, Saudi Arabia and Rabin Gyawali, Food and Nutritional Sciences, North Carolina A & T State University, Greensboro
Salam Ibrahim, Food and Nutritional Sciences, North Carolina A & T State University, Greensboro, NC, Sulaiman Aljaloud, Department of Exercise Physiology, King Saud University,, Riyadh, Saudi Arabia and Rabin Gyawali, Food and Nutritional Sciences, North Carolina A & T State University, Greensboro
Two New Cyclic Peptides from Marine Cyanobacteria
Ozlem Demirkiran1, Gabriel Navarro2, John Lee2, Paul Boudreau2 and William H. Gerwick2, (1)Faculty of Pharmacy, Department of Pharmacognosy, Trakya University, Edirne-TURKEY, (2)Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA
Ozlem Demirkiran1, Gabriel Navarro2, John Lee2, Paul Boudreau2 and William H. Gerwick2, (1)Faculty of Pharmacy, Department of Pharmacognosy, Trakya University, Edirne-TURKEY, (2)Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA
Novel roles for antibiotic metabolites localized at the cell surface during inter-species bacterial competition
Chris Hoefler and Paul Straight, Biochemistry and Biophysics, Texas A&M University, College Station, TX
Chris Hoefler and Paul Straight, Biochemistry and Biophysics, Texas A&M University, College Station, TX
Novel Antimicrobial Cyclic Depsipeptides from a Terrestrial Streptomyces sp. 13F003
Mr. Sangkeun Son1, Dr. Sung-Kyun Ko2, Young-Soo Hong3, Dr. Jae-Hyuk Jang2 and Jong-Seog Ahn2, (1)Major of Biomolecular Science, University of Science and Technology, Daejeon, (2)Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, (3)Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Chungbuk
Mr. Sangkeun Son1, Dr. Sung-Kyun Ko2, Young-Soo Hong3, Dr. Jae-Hyuk Jang2 and Jong-Seog Ahn2, (1)Major of Biomolecular Science, University of Science and Technology, Daejeon, (2)Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, (3)Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Chungbuk
New oxazoline-containing tetrapeptides from a marine-derived Streptomyces sp., strain CNX-225
Marina Scopel, Vimal Nair and William Fenical, Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, La Jolla, CA
Marina Scopel, Vimal Nair and William Fenical, Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, La Jolla, CA
A Novel Glycosylated Macrolide from a Rare Actinomycete, Catenulispora sp. 13F217
Mr. Gil Soo Kim1, Mr. Sangkeun Son2, Dr. Sung-Kyun Ko2, Dr. Jae-Hyuk Jang2 and Jong-Seog Ahn2, (1)Major of Biomolecular Science, University of Science and Technology, Daejeon, (2)Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju
Mr. Gil Soo Kim1, Mr. Sangkeun Son2, Dr. Sung-Kyun Ko2, Dr. Jae-Hyuk Jang2 and Jong-Seog Ahn2, (1)Major of Biomolecular Science, University of Science and Technology, Daejeon, (2)Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju
Geumsanols, Highly Oxygenated Azaphilones Produced by Penicillium sp. 11A109 from a Ginseng Field
Dr. Jae-Hyuk Jang1, Mr. Sangkeun Son1, Mr. Jong Won Kim1, Young-Soo Hong2 and Jong-Seog Ahn1, (1)Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, (2)Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Chungbuk, South Korea
Dr. Jae-Hyuk Jang1, Mr. Sangkeun Son1, Mr. Jong Won Kim1, Young-Soo Hong2 and Jong-Seog Ahn1, (1)Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, (2)Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Chungbuk, South Korea
Isolation and Structural Determination of New Pyridone Alkaloids from a fungus Chaunopycnis sp. 13ETF032
Mr. Jong Won Kim, Dr. Sung-Kyun Ko, Dr. Jae-Hyuk Jang and Jong-Seog Ahn, Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju
Mr. Jong Won Kim, Dr. Sung-Kyun Ko, Dr. Jae-Hyuk Jang and Jong-Seog Ahn, Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju
Mapping the molecular universe of marine cyanobacterial natural products
Tal Luzzatto Knaan1, Neha Garg1, Yao Peng1, Theodore Alexandrov1, Evgenia Glukhov2, Lena G. Gerwick2, William H. Gerwick2 and Pieter C. Dorrestein3, (1)Skaggs School of Pharmacy & Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA, (2)Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA, (3)Skaggs School of Pharmacy & Pharmaceutical Sciences, University of California San Diego, La Jolla, CA
Tal Luzzatto Knaan1, Neha Garg1, Yao Peng1, Theodore Alexandrov1, Evgenia Glukhov2, Lena G. Gerwick2, William H. Gerwick2 and Pieter C. Dorrestein3, (1)Skaggs School of Pharmacy & Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA, (2)Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA, (3)Skaggs School of Pharmacy & Pharmaceutical Sciences, University of California San Diego, La Jolla, CA
Search for circumventors of arbekacin resistance in MRSA
Mr. Takuya Suga1, Ms. Mayu Shiina1, Dr. Masato Iwatsuki2, Dr. Tsuyoshi Yamamoto2, Dr. Kenichi Nonaka2, Dr. Rokuro Masuma2, Mr. Hidehito Matsui2, Prof. Hideaki Hanaki2, Prof. Satoshi Omura2 and Prof. Kazuro Shiomi2, (1)Graduate School of Infection Control Sciences, Kitasato University, Tokyo, (2)Kitasato Institute for Life Sciences, Kitasato University, Tokyo
Mr. Takuya Suga1, Ms. Mayu Shiina1, Dr. Masato Iwatsuki2, Dr. Tsuyoshi Yamamoto2, Dr. Kenichi Nonaka2, Dr. Rokuro Masuma2, Mr. Hidehito Matsui2, Prof. Hideaki Hanaki2, Prof. Satoshi Omura2 and Prof. Kazuro Shiomi2, (1)Graduate School of Infection Control Sciences, Kitasato University, Tokyo, (2)Kitasato Institute for Life Sciences, Kitasato University, Tokyo
Simplifungin, a new antifungal antibiotic produced by Simplicillium minatense FKI-4981
Dr. Ryuji Uchida1, Mr. Hirohyuki Ishijima1, Ms. Ariko Kondo1, Dr. Masaki Ohtawa1, Dr. Kenichiro Nagai1, Dr. Kenichi Nonaka2, Dr. Rokuro Masuma2, Prof. Tohru Nagamitsu1 and Prof. Hiroshi Tomoda1, (1)Graduate School of Pharmaceutical Sciences, Kitasato University, Tokyo, (2)Kitasato Institute for Life Sciences, Kitasato University, Tokyo
Dr. Ryuji Uchida1, Mr. Hirohyuki Ishijima1, Ms. Ariko Kondo1, Dr. Masaki Ohtawa1, Dr. Kenichiro Nagai1, Dr. Kenichi Nonaka2, Dr. Rokuro Masuma2, Prof. Tohru Nagamitsu1 and Prof. Hiroshi Tomoda1, (1)Graduate School of Pharmaceutical Sciences, Kitasato University, Tokyo, (2)Kitasato Institute for Life Sciences, Kitasato University, Tokyo
Bacterial heme synthetic pathway: determination of the bottleneck steps
Pil Kim, Biotechnology, the Catholic University of Korea, Bucheon, Gyeonggi
Pil Kim, Biotechnology, the Catholic University of Korea, Bucheon, Gyeonggi
Elucidation of specific interaction between the model organism Aspergillus nidulans and Streptomycetes
Tina Netzker, Leibniz Institute for Natural Product Research and Infection Biology - Hans-Knoell-Institute (HKI), Department of Molecular and Applied Microbiology, Jena, Volker Schroeckh, Department of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology - Hans-Knoell-Institute (HKI), Jena and Axel A. Brakhage, Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute, Jena, Germany
Tina Netzker, Leibniz Institute for Natural Product Research and Infection Biology - Hans-Knoell-Institute (HKI), Department of Molecular and Applied Microbiology, Jena, Volker Schroeckh, Department of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology - Hans-Knoell-Institute (HKI), Jena and Axel A. Brakhage, Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute, Jena, Germany
The production of antibiotics by Streptomyces after actinomycete-actinomycete interaction with Pseudonocardia sp. PIP161 characterized by increased sporulation
Rio Risandiansyah1, Michael V. Perkins2 and Christopher M.M. Franco1, (1)School of Medicine, Flinders University, Adelaide, (2)School of Chemical and Physical Sciences, Flinders University, Adelaide
Rio Risandiansyah1, Michael V. Perkins2 and Christopher M.M. Franco1, (1)School of Medicine, Flinders University, Adelaide, (2)School of Chemical and Physical Sciences, Flinders University, Adelaide
Amphotericin B as part of a chemical complex behind two endophytic microorganisms interaction
Andres Caraballo1, Monica Pupo1 and Pieter C. Dorrestein2, (1)School of Pharmaceutical Sciences of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, (2)Skaggs School of Pharmacy & Pharmaceutical Sciences, University of California San Diego, La Jolla, CA
Andres Caraballo1, Monica Pupo1 and Pieter C. Dorrestein2, (1)School of Pharmaceutical Sciences of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, (2)Skaggs School of Pharmacy & Pharmaceutical Sciences, University of California San Diego, La Jolla, CA
Ecology and taxonomy driven discovery of new bioactive natural products
Jens Frisvad, Department of Systems Biology, Technical University of Denmark, Kongens Lyngby
Jens Frisvad, Department of Systems Biology, Technical University of Denmark, Kongens Lyngby
Antitermination control of bacterial antibiotic gene clusters
Paul Straight, Biochemistry and Biophysics, Texas A&M University, College Station, TX and Wade Winkler, Cell Biology and Molecular Genetics, University of Maryland
Paul Straight, Biochemistry and Biophysics, Texas A&M University, College Station, TX and Wade Winkler, Cell Biology and Molecular Genetics, University of Maryland
Application of NMR-based Metabolomics for the discovery of novel antibiotics produced by actinomycetes
Chang-Sheng Wu1, Young Hae Choi1 and Gilles van Wezel2, (1)Institute of Biology, Leiden University, Sylviusweg 72, (2)Molecular Biotechnology, Leiden University, Leiden, The Netherlands
Chang-Sheng Wu1, Young Hae Choi1 and Gilles van Wezel2, (1)Institute of Biology, Leiden University, Sylviusweg 72, (2)Molecular Biotechnology, Leiden University, Leiden, The Netherlands
Activation of the silent actinorhodin gene cluster of Streptomyces lividans by DNA fragments from Saccharopolyspora erythraea
Mark Weber, Minh Luu, Kristin Bergsland, Paul Hessler, Peter Larsen and Roy Wesley, Fermalogic, Inc., Chicago, IL
Mark Weber, Minh Luu, Kristin Bergsland, Paul Hessler, Peter Larsen and Roy Wesley, Fermalogic, Inc., Chicago, IL
Secondary metabolite induction by mycolic acid-containing bacteria in Streptomyces
Shumpei Asamizu1, Taro Ozaki2 and Hiroyasu Onaka2, (1)Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, (2)Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan
Shumpei Asamizu1, Taro Ozaki2 and Hiroyasu Onaka2, (1)Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, (2)Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan
Characterization of the mechanism for the goadsporin self-resistance
Taro Ozaki1, Shumpei Asamizu2 and Hiroyasu Onaka1, (1)Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan, (2)Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo
Taro Ozaki1, Shumpei Asamizu2 and Hiroyasu Onaka1, (1)Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan, (2)Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo
First characterisation of a type III PKS gene cluster from cyanobacteria
Dr. Rabia Mazmouz, Dr. Rocky Chau and Prof. Brett A. Neilan, School of Biotechnology and Biomolecular Science, University of New South Wales, Sydney
Dr. Rabia Mazmouz, Dr. Rocky Chau and Prof. Brett A. Neilan, School of Biotechnology and Biomolecular Science, University of New South Wales, Sydney
Artificial biosynthesis of resveratrol derivatives in a tyrosine overproducing Escherichia coli strain
Young-Soo Hong1, Sun-Young Kang1, Jae Kyoung Lee2 and Oksik Choi1, (1)Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Chungbuk, South Korea, (2)Korea Research Institute of Bioscience and Biotechnology, Chemical Biology Research Center, Chungbuk
Young-Soo Hong1, Sun-Young Kang1, Jae Kyoung Lee2 and Oksik Choi1, (1)Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Chungbuk, South Korea, (2)Korea Research Institute of Bioscience and Biotechnology, Chemical Biology Research Center, Chungbuk
Complex secondary metabolite potential of the group V cyanobacteria revealed through whole genome sequencing
Melinda L. Micallef1, Paul M. D'Agostino2, Deepti Sharma3, Rajesh Viswanathan3 and Michelle C Moffitt.1, (1)School of Science and Health, University of Western Sydney, Penrith, (2)School of Biotechnology and Biomolecular Sciences, University of New South Wales, (3)Department of Chemistry, Case Western Reserve University
Melinda L. Micallef1, Paul M. D'Agostino2, Deepti Sharma3, Rajesh Viswanathan3 and Michelle C Moffitt.1, (1)School of Science and Health, University of Western Sydney, Penrith, (2)School of Biotechnology and Biomolecular Sciences, University of New South Wales, (3)Department of Chemistry, Case Western Reserve University
Genomes to Natural Products and Back
Nathan A. Magarvey, Department of Biochemistry and Biomedical Sciences and Chemistry & Chemical Biology, The Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, ON, Canada
Nathan A. Magarvey, Department of Biochemistry and Biomedical Sciences and Chemistry & Chemical Biology, The Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, ON, Canada
Characterization of an aryl polyene biosynthetic gene cluster superfamily widespread among Gram-negative bacteria
Dr. Jan Claesen and Michael Fischbach, Department of Bioengineering and Therapeutic Sciences and California Institute for Quantitative Biosciences, University of California, San Francisco, San Francisco, CA
Dr. Jan Claesen and Michael Fischbach, Department of Bioengineering and Therapeutic Sciences and California Institute for Quantitative Biosciences, University of California, San Francisco, San Francisco, CA
Natural products discovery, genome mining and the NPDI collection
John Ondeyka, Janet Sigmund, Tina Gill, Jason Clement and Mike Goetz, Blumberg Institute, Doylestown
John Ondeyka, Janet Sigmund, Tina Gill, Jason Clement and Mike Goetz, Blumberg Institute, Doylestown
A promising chassis derived from Streptomyces sp. FR-008 and its development for polyketide derived natural products heterologous overproduction system
Dr. Qian Liu, Yuanjie Zhou, Prof. Tiangang Liu and Prof. Zixin Deng, School of Pharmaceutical Sciences, Wuhan University, Wuhan
Dr. Qian Liu, Yuanjie Zhou, Prof. Tiangang Liu and Prof. Zixin Deng, School of Pharmaceutical Sciences, Wuhan University, Wuhan
Metagenomic tools to assess the diversity of polyketide synthases in the underground river of the Yucatan peninsula
Alejandra Prieto-Davo1, Miguel Marfil-Santana2, Korynthia Lopez-Aguiar1, César delosSantos-Briones2 and Aileen O'Connor-Sánchez2, (1)Facultad de Química, Unidad Sisal, Universidad Nacional Autónoma de México, Sisal, (2)Biotechnology, Centro de Investigación Científica y Tecnológica de Yucatán, A.C., Mérida
Alejandra Prieto-Davo1, Miguel Marfil-Santana2, Korynthia Lopez-Aguiar1, César delosSantos-Briones2 and Aileen O'Connor-Sánchez2, (1)Facultad de Química, Unidad Sisal, Universidad Nacional Autónoma de México, Sisal, (2)Biotechnology, Centro de Investigación Científica y Tecnológica de Yucatán, A.C., Mérida
Transcriptome analysis of antibiotic-producing Bacillus subtilis SC-8 using RNA-seq provoked by small peptides from wild type and PapR mutant of Bacillus cereus strains
Young Tae Hahm1, In-Cheol Yeo2, Chandra Datta Sumi1 and Byung Wook Yang1, (1)Systems Biotechnology, Chung-Ang University, Anseong, Republic of KOREA, (2)Biochemistry and Biophysics, Texas A&M University, College Station TX 77843, USA
Young Tae Hahm1, In-Cheol Yeo2, Chandra Datta Sumi1 and Byung Wook Yang1, (1)Systems Biotechnology, Chung-Ang University, Anseong, Republic of KOREA, (2)Biochemistry and Biophysics, Texas A&M University, College Station TX 77843, USA
Algorithmic DNA assembly methods for rapidly engineering multi-gene systems
Michael Smanski1, Maciej Maselko2, Duc Hoang2 and Stephen Heinsch2, (1)Biochemistry, University of Minnesota, St. Paul, MN, (2)University of Minnesota
Michael Smanski1, Maciej Maselko2, Duc Hoang2 and Stephen Heinsch2, (1)Biochemistry, University of Minnesota, St. Paul, MN, (2)University of Minnesota
Discovery of secondary metabolites from Bacillus spp. biocontrol strains using genome mining and mass spectroscopy
Christopher Dunlap1, Michael J. Bowman2 and David Schisler1, (1)Crop Bioprotection Research Unit, Peoria, IL, (2)Bioenergy Research Unit, United States Department of Agriculture, Agricultural Research Service, National Center for Agricultural Utilization Research, Peoria, IL
Christopher Dunlap1, Michael J. Bowman2 and David Schisler1, (1)Crop Bioprotection Research Unit, Peoria, IL, (2)Bioenergy Research Unit, United States Department of Agriculture, Agricultural Research Service, National Center for Agricultural Utilization Research, Peoria, IL
Genome mining of Salinispora sp strains isolated from the São Pedro and São Paulo Archipelago in Brazil
Ms. Karine Pires, Instituto de Ciências do Mar - LABOMAR, pHD student/Universidade Federal do Ceará, Fortaleza, Ms. Michelle Schorn, Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, pHD student/University of California - San Diego, Dr. Max Crüesemann, Center for Marine Biotechnology and Biomedicine,, Scripps Institution of Oceanography, La Jolla, CA, Mr. Elthon Goes Ferreira, Instituto de Ciências do Mar - LABOMAR, pHD student/Universidade Federal do Ceará, Dr. Letícia Veras Costa-Lotufo, Instituto de Ciências do Mar - LABOMAR and Departamento de Fisiologia e Farmacologia, Professor/Universidade Federal do Ceará and Dr. Bradley S. Moore, Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, San Diego
Ms. Karine Pires, Instituto de Ciências do Mar - LABOMAR, pHD student/Universidade Federal do Ceará, Fortaleza, Ms. Michelle Schorn, Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, pHD student/University of California - San Diego, Dr. Max Crüesemann, Center for Marine Biotechnology and Biomedicine,, Scripps Institution of Oceanography, La Jolla, CA, Mr. Elthon Goes Ferreira, Instituto de Ciências do Mar - LABOMAR, pHD student/Universidade Federal do Ceará, Dr. Letícia Veras Costa-Lotufo, Instituto de Ciências do Mar - LABOMAR and Departamento de Fisiologia e Farmacologia, Professor/Universidade Federal do Ceará and Dr. Bradley S. Moore, Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, San Diego
Genome-guided natural product discovery from an octopus-derived Pseudoalteromonas species
Dr. Rocky Chau, Dr. John A. Kalaitzis and Prof. Brett A. Neilan, School of Biotechnology and Biomolecular Science, University of New South Wales, Sydney
Dr. Rocky Chau, Dr. John A. Kalaitzis and Prof. Brett A. Neilan, School of Biotechnology and Biomolecular Science, University of New South Wales, Sydney
Combining Mass Spectrometric Metabolic Profiling with Genomic Analysis: A Powerful Tool for Revealing New Natural Products in Cyanobacteria
Karin Kleigrewe, Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, Isaac Yuheng Tian, University of California Berkeley, Robin B. Kinnel, Hamilton College, Clinton, NY, Anton Korobeynikov, Saint Petersburg State University, Pavel Pevzner, Department of Computer Science and Engineering, University of California San Diego, David H. Sherman, Life Sciences Institute & Associate Dean for Research and Graduate Education, University of Michigan, Ann Arbor, MI, Pieter C. Dorrestein, Skaggs School of Pharmacy & Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, Lena Gerwick, Gerwick Laboratory, Scripps Institution of Oceanography, San Diego, CA and William Gerwick, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA
Karin Kleigrewe, Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, Isaac Yuheng Tian, University of California Berkeley, Robin B. Kinnel, Hamilton College, Clinton, NY, Anton Korobeynikov, Saint Petersburg State University, Pavel Pevzner, Department of Computer Science and Engineering, University of California San Diego, David H. Sherman, Life Sciences Institute & Associate Dean for Research and Graduate Education, University of Michigan, Ann Arbor, MI, Pieter C. Dorrestein, Skaggs School of Pharmacy & Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, Lena Gerwick, Gerwick Laboratory, Scripps Institution of Oceanography, San Diego, CA and William Gerwick, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA
PRISM: a computational resource for genomic natural product discovery
Michael A. Skinnider1, Chris Dejong2, Phil Rees2, Chad W. Johnston3, Andrew L.H. Webster4 and Nathan Magarvey5, (1)McMaster University, Hamilton, ON, (2)Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON, (3)Department of Biochemistry and Biomedical Sciences, The Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, ON, Canada, (4)Department of Biochemistry and Biomedical Sciences; Department of Chemistry and Chemical Biology, McMaster University, Hamilton, ON, (5)Department of Biochemistry and Biomedical Sciences & Chemistry and Chemical Biology, McMaster University, Hamilton, ON, Canada
Michael A. Skinnider1, Chris Dejong2, Phil Rees2, Chad W. Johnston3, Andrew L.H. Webster4 and Nathan Magarvey5, (1)McMaster University, Hamilton, ON, (2)Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON, (3)Department of Biochemistry and Biomedical Sciences, The Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, ON, Canada, (4)Department of Biochemistry and Biomedical Sciences; Department of Chemistry and Chemical Biology, McMaster University, Hamilton, ON, (5)Department of Biochemistry and Biomedical Sciences & Chemistry and Chemical Biology, McMaster University, Hamilton, ON, Canada
Complete Microbial Genomes, Epigenomes, and Transcriptomes using Long-Read PacBio Sequencing
Dr. Tyson Clark, Pacific Biosciences, Menlo Park, CA
Dr. Tyson Clark, Pacific Biosciences, Menlo Park, CA
BIRD: a comprehensive database for the storage and manipulation of genetic information and natural products
Phil Rees and Chris Dejong, Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON
Phil Rees and Chris Dejong, Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON
The potential of Dictyostelium discoideum for natural product and antimicrobial discovery
Dr. Rafael Rosengarten1, Christopher Dinh2, Dr. Adam Kuspa2 and Prof. Gad Shaulsky1, (1)Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, (2)Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX
Dr. Rafael Rosengarten1, Christopher Dinh2, Dr. Adam Kuspa2 and Prof. Gad Shaulsky1, (1)Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, (2)Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX
Siderophore Evolution and Functional Pathway Swapping in the Marine Actinomycete Genus Salinispora
Dr. Nadine Ziemert1, Dr. Max Crüesemann2, Paul R. Jensen3 and Bradley Moore3, (1)Scripps Institution of Ocenaography, University of California, San Diego, La Jolla, CA, (2)Center for Marine Biotechnology and Biomedicine,, Scripps Institution of Oceanography, La Jolla, CA, (3)Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, La Jolla, CA
Dr. Nadine Ziemert1, Dr. Max Crüesemann2, Paul R. Jensen3 and Bradley Moore3, (1)Scripps Institution of Ocenaography, University of California, San Diego, La Jolla, CA, (2)Center for Marine Biotechnology and Biomedicine,, Scripps Institution of Oceanography, La Jolla, CA, (3)Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, La Jolla, CA
Genomic analyses of the three extremely halophilic archaea using next-generation sequencing
Dr. Jin-Kyu Rhee1, Dr. Jongyoun Cho2, Dr. Joseph Kwon3, Prof. Duwoon Kim2, Prof. Jong-Soon Choi3 and Dr. Seong Woon Roh4, (1)Western Seoul Center, Korea Basic Science Institute, Seoul, Republic of Korea, (2)Department of Food Science and Technology and Functional Food Research Center, Chonnam National University, Gwangju, Republic of Korea, (3)Division of Life Science, Korea Basic Science Institute, Daejeon, Republic of Korea, (4)Jeju Center, Korea Basic Science Institute, Jeju, Republic of Korea
Dr. Jin-Kyu Rhee1, Dr. Jongyoun Cho2, Dr. Joseph Kwon3, Prof. Duwoon Kim2, Prof. Jong-Soon Choi3 and Dr. Seong Woon Roh4, (1)Western Seoul Center, Korea Basic Science Institute, Seoul, Republic of Korea, (2)Department of Food Science and Technology and Functional Food Research Center, Chonnam National University, Gwangju, Republic of Korea, (3)Division of Life Science, Korea Basic Science Institute, Daejeon, Republic of Korea, (4)Jeju Center, Korea Basic Science Institute, Jeju, Republic of Korea
Genome Sequencing and RNA Sequencing Analysis of Streptomyces hygroscopicus ATCC 29253 & Its Rapamycin-Hyperproducing Mutant
Sung Hyun Moon1, Dong-Hoon Yoon1, Seong-Seon Yu1, Young Ji Yoo2, Prof. Yeo Joon Yoon2, Byoung-Kook Kim1 and Jung Woo Suh1, (1)Research Institute, CKDBiO Corporation, Ansan, South Korea, (2)Department of Chemistry and Nano Science, Ewha Womans University, Seoul, South Korea
Sung Hyun Moon1, Dong-Hoon Yoon1, Seong-Seon Yu1, Young Ji Yoo2, Prof. Yeo Joon Yoon2, Byoung-Kook Kim1 and Jung Woo Suh1, (1)Research Institute, CKDBiO Corporation, Ansan, South Korea, (2)Department of Chemistry and Nano Science, Ewha Womans University, Seoul, South Korea
Annotation of secondary metabolite biosynthetic genes in Bacillus thuringiensis genomes
Don Hahn, Dow AgroSciences LLC, Indianapolis, IN, Premchand Gandra, Dow AgroSciences and Ying Sha, Georgia Tech
Don Hahn, Dow AgroSciences LLC, Indianapolis, IN, Premchand Gandra, Dow AgroSciences and Ying Sha, Georgia Tech
Identifying Salinispora Orphan Biosynthetic Pathways by Direct cloning and Heterologous Expression
Dr. Xiaoyu Tang1, Dr. Jie Li1, Jia Jia Zhang1, Dr. Nadine Ziemert1 and Bradley Moore2, (1)Scripps Institution of Ocenaography, University of California, San Diego, La Jolla, CA, (2)Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla
Dr. Xiaoyu Tang1, Dr. Jie Li1, Jia Jia Zhang1, Dr. Nadine Ziemert1 and Bradley Moore2, (1)Scripps Institution of Ocenaography, University of California, San Diego, La Jolla, CA, (2)Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla
Genome mining reveals a minimum gene set for the biosynthesis of lactazoles, novel 32-membered macrocyclic thiopeptides
Dr. Shohei Hayashi1, Taro Ozaki2, Shumpei Asamizu1 and Hiroyasu Onaka2, (1)Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, (2)Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan
Dr. Shohei Hayashi1, Taro Ozaki2, Shumpei Asamizu1 and Hiroyasu Onaka2, (1)Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, (2)Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan
GRAPE: Matching natural products with gene clusters
Chris Dejong1, Greg Chen2, Phil Rees1 and Michael Skinnider3, (1)Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON, (2)Health Sciences, McMaster University, Hamilton, ON, (3)McMaster University, Hamilton, ON
Chris Dejong1, Greg Chen2, Phil Rees1 and Michael Skinnider3, (1)Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON, (2)Health Sciences, McMaster University, Hamilton, ON, (3)McMaster University, Hamilton, ON
Cloning and heterologous expression of six orphan gene clusters from Streptomyces sp. CNB091
Simone Moraes Mantovani, Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, Kazuya Murata, University of California San diego, la Jolla, CA, Dr. Nadine Ziemert, Scripps Institution of Ocenaography, University of California, San Diego, La Jolla, CA and Bradley Moore, Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, La Jolla, CA
Simone Moraes Mantovani, Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA, Kazuya Murata, University of California San diego, la Jolla, CA, Dr. Nadine Ziemert, Scripps Institution of Ocenaography, University of California, San Diego, La Jolla, CA and Bradley Moore, Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, La Jolla, CA
Discovery and linking of genes to biosynthetic pathways in Aspergillus
Thomas Ostenfeld Larsen, Department of Systems Biology, Technical University of Denmark, Kgs. Lyngby
Thomas Ostenfeld Larsen, Department of Systems Biology, Technical University of Denmark, Kgs. Lyngby
Developing of Streptomyces as Super Host for Natural Product Overproduction
Prof. Tiangang Liu, School of Pharmaceutical Sciences, Wuhan University, Wuhan
Prof. Tiangang Liu, School of Pharmaceutical Sciences, Wuhan University, Wuhan
Microaerophilic conditions cue secondary metabolite variability in a marine-derived Streptomyces strain
Kelley Gallagher1, Greg Wanger1 and Paul Jensen2, (1)University of California, San Diego, Scripps Institution of Oceanography, La Jolla, CA, (2)Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, La Jolla, CA
Kelley Gallagher1, Greg Wanger1 and Paul Jensen2, (1)University of California, San Diego, Scripps Institution of Oceanography, La Jolla, CA, (2)Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, La Jolla, CA
Improvement of platensimycin and platencin production and their activities against clinical methicillin-resistant Staphylococcus aureus isolates in China
Yong Huang1, Nan Ren2, Xiangcheng Zhu1, Jun Shi3, Ling Liu3, Ben Shen4 and Yanwen Duan1, (1)Xiangya International Academy of Translational Medicine, Central South University; Hunan Engineering Research Center of Combinatorial Biosynthesis and Natural Product Drug Discovery, Changsha, (2)Xiangya International Academy of Translational Medicine and Xiangya Hospital, Central South University, Changsha, Changsha, (3)Xiangya International Academy of Translational Medicine, Central South University, Changsha, (4)Departments of Chemistry and Molecular Therapeutics, and The Natural Products Library Initiative at TSRI, The Scripps Research Institute, Jupiter, FL
Yong Huang1, Nan Ren2, Xiangcheng Zhu1, Jun Shi3, Ling Liu3, Ben Shen4 and Yanwen Duan1, (1)Xiangya International Academy of Translational Medicine, Central South University; Hunan Engineering Research Center of Combinatorial Biosynthesis and Natural Product Drug Discovery, Changsha, (2)Xiangya International Academy of Translational Medicine and Xiangya Hospital, Central South University, Changsha, Changsha, (3)Xiangya International Academy of Translational Medicine, Central South University, Changsha, (4)Departments of Chemistry and Molecular Therapeutics, and The Natural Products Library Initiative at TSRI, The Scripps Research Institute, Jupiter, FL
Hijacking thiocillin biosynthesis to build new antibiotics
Hai L. Tran1, Michael Fischbach2, Christopher T. Walsh3 and James A. Wells1, (1)Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, (2)Department of Bioengineering and Therapeutic Sciences and California Institute for Quantitative Biosciences, University of California, San Francisco, San Francisco, CA, (3)Department of Biological Chemistry & Molecular Pharmacology, Harvard Medical School, Boston, MA
Hai L. Tran1, Michael Fischbach2, Christopher T. Walsh3 and James A. Wells1, (1)Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, (2)Department of Bioengineering and Therapeutic Sciences and California Institute for Quantitative Biosciences, University of California, San Francisco, San Francisco, CA, (3)Department of Biological Chemistry & Molecular Pharmacology, Harvard Medical School, Boston, MA
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