Development of a protease activity tool kit for the identification and characterization of native Pichia pastoris proteases
Christopher Kistler¹, Jeffrey Bernstein², Juergen Nett³, Briana Hecht⁴, James Park⁴, Rachel Bareither¹ and Thomas I. Potgieter⁵, (1)Biologics New and Enabling Technologies, Merck & Co., Inc, Rahway, NJ, (2)Bioprocess Research and Development, Merck & Co., Rahway, NJ, (3)GlycoFi, a wholly owned subsidiary of Merck & Co Inc., Lebanon, NH, (4)Bioprocess Development, Merck & Co., Inc, Rahway, NJ, (5)Biologics New and Enabling Technologies, Merck & Co Inc., Rahway, NJ

Luminescent Dissolved Oxygen Probe with Unique Capabilities
Ruby N. Ghosh¹, Reza Loloee¹, James Wynn², Michael V. Guettler² and Denise S. Rumler², (1)Physics, Michigan State University, East Lansing, MI, (2)MBI, Lansing, MI

From Protein Drug Discovery to Clinical Evaluation Completely within an Academic Setting
Everett M. Stone¹, Jung-Hee Woo², Arthur E. Frankel² and George Georgiou³, (1)Biomedical Eng, University of Texas,, Austin, TX, (2)Cancer Research Institute, Scott & White, Temple, TX, (3)Cockrell Chair in Engineering, Depts of Chemical Eng., Biomedical Eng. and Molecular Genetics and Microbiology, University of Texas, Austin, TX

Break

Enhancing bioprocess productivity through dynamic control of gene expression
Nikolaos Anesiadis¹, Hideki Kobayashi², William R. Cluett¹ and Radhakrishnan Mahadevan¹, (1)Chemical Engineering & Applied Chemistry, University of Toronto, Toronto, ON, Canada, (2)Extremobiosphere Research Center (XBR), Japan Agency for Marine-Earth Science and Technology (JAMSTEC), Yokosuka, Japan

Biochemical profiling and analysis in process development and scale up to improve overall productivity
Adam Kennedy, Scientific Study Design, Metabolon, Inc., Durham, NC