S8: Emerging Technologies for Improved Fermentation Management

For many years the bioprocess industry has taken the needs of fermentation         applications for granted, often choosing instead to focus on those of cell culture and the    resulting technologies handed down to fermentation.  Recently, this has begun to     change as the challenging aspects of fermentation management are increasingly             recognized while at the same time industry interest in fermentation applications is on     the rise.  The result is a new era of hard and soft technology, known collectively as PAT.

            In this discussion we will explore the leading hard and soft technologies that are defining PAT for fermentation applications.  This will include emerging hardware    technology such as sensors that are enabling the real-time continuous measurement of          the fermentation process and software technology such as DoE that is leveraging the             information from these sensors to deliver QbD.  We will also explore how proven             technologies are evolving in their capabilities to play a role in PAT, DoE and QbD for the             purpose of improving fermentation management.