Session 30: Industrialization of synthetic biology and metabolic engineering
Thursday, July 28, 2016: 8:00 AM-11:30 AM
Waterbury, 2nd Fl (Sheraton New Orleans)
Reshma Shetty - Ginkgo Bioworks
Ken Bruno - Zymergen
The process of bioengineering of microbes for industrial production of chemicals and enzymes has largely been an empirical process to date.  New technologies including automation, computation, wetware tools, advanced analytics and CAD/CAM software are leading to the systematization and industrialization of genetic engineering.  This session will cover the challenges and successes in moving projects from the bench to large scale industrial fermentation and identify new areas for investment going forward.
8:00 AM
A systems and cell biological approach to biodesign in the oleaginous yeast, Yarrowia lipolytica
Scott E. Baker1, Ziyu Dai2, Kyle Pomraning1 and Erin Bredeweg1, (1)Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, WA, (2)Chemical and Biological Process Development, Pacific Northwest National Laboratory, Richland, WA
8:30 AM
Automated, predictive, scalable design and efficient optimization of many-enzyme genetic systems
Howard Salis, Chemical Engineering / Biological Engineering, Penn State University, University Park, PA
9:00 AM
Stepping on the gas: the industrialization of methanotroph biology
James Kealey, Industrial Products Division, Intrexon Corporation, South San Francisco, CA
9:30 AM
Break, Grand Ballroom Foyer 5th Fl
10:00 AM
Optogenetics switches: tunable tools to control gene expression and biotechnologically relevant phenotypes in Saccharomyces cerevisiae
Luis Larrondo, Francisco Salinas, Vicente Rojas, Veronica Delgado and Eduardo Agosin, Departamento de Genetica Molecular y Microbiologia, Millennium Nucleus for Fungal Integrative and Synthetic Biology. Pontificia Universidad Catolica de Chile, Santiago, Chile
10:30 AM
High throughput industrial microbiology in non-canonical systems
Kenneth S. Bruno, Patrick J. Westfall, Kyle Rothschild-Mancinelli, Jack Cunha, Thomas P. Treynor, Jason Kintz, Christine M. Roche, Ray Nagatani, Jed Dean and Zach Serber, Zymergen, Inc, Emeryville, CA
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