Session 26: Synthetic Biology: Computerization of Biodesign
Thursday, July 24, 2014: 8:30 AM-11:30 AM
Regency Ballroom A, Second Floor (St. Louis Hyatt Regency at the Arch)
Convener:
J. Christopher Anderson - University of California, Berkeley, Berkeley, CA
The way we design genetic constructs, reduce them to a physical form, and analyze their function in cells is becoming increasingly computerized and automated. This transition from ad hoc methods is driven by software such as design tools that compute potential designs from biochemical data, design of experiment methods for optimally choosing the datapoints to test, design of regulatory element sequences, and optimization of coding sequences. These advances in design are coupled with automated manufacturing software and robotic pipelines for fabricating DNAs from large microarray oligo sets, assembling combinations of genes into larger constructs, and characterization of constructs. In this session, we'll explore the most recent advances in this emerging topic of biodesign.

8:30 AM
S130
Computational design of enzymatic pathways using the Act Synthesizer
Saurabh Srivastava1, Paul Ruan1, Jeff Tsui1, Tim Hsiau1, Sarah Chasins1, Jonathan Kotker1, Jene Li1, Sridatta Thatipamalla1, Sanjit A. Seshia1, Rastislav Bodik1 and J. Christopher Anderson2, (1)Eecs, UC Berkeley, Berkeley, CA, (2)University of California, Berkeley, Berkeley, CA
9:00 AM
S131
DIVA: DNA design, implementation, and verification automation platform
Nathan Hillson, Joanna Chen, Hector Plahar, Nina Stawski, Garima Goyal and Jay D. Keasling, Fuels Synthesis - Synthetic Biology, Joint BioEnergy Institute, Emeryville, CA
10:00 AM
S132
Design and Optimization of a Synthetic Pathway for Improved & Controllable NADPH Regeneration
Chiam Yu Ng1, Iman Farasat1, Costas Maranas2 and Howard Salis1, (1)Penn State Univ, University Park, PA, (2)ChE, PSU, University Park, PA
10:30 AM
S133
Integration and holes in the BioCAD toolchain
J. Christopher Anderson, University of California, Berkeley, Berkeley, CA
See more of: Invited Oral Papers
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