Session 7: Novel Enzyme Mechanisms in Biosynthesis
Monday, July 21, 2014: 1:00 PM-4:30 PM
Regency Ballroom EF, Second Floor (St. Louis Hyatt Regency at the Arch)
Wenjun Zhang - UC Berkeley, Berkeley, CA
Natural products are produced by dedicated metabolic pathways using enzymes that possess exquisite catalytic power. This session will focus on recent discoveries in novel enzyme mechanisms in biosynthesis of natural products. Characterization of these enzymes will facilitate biosynthesis of natural products and their analogues, and promote new natural product discovery.

1:00 PM
Terminal alkene and alkyne biosynthesis in microbes
Wenjun Zhang, Chemical and Biomolecular Engineering, UC Berkeley, Berkeley, CA
1:30 PM
Cytochrome P450 as Dimerization Catalyst in Diketopiperazine Alkaloid Biosynthesis
Kenji Watanabe, Department of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan
2:00 PM
Chemical Discovery in the Microbial World
Emily P. Balskus, Department of Chemistry & Chemical Biology, Harvard University, Cambridge, MA
3:00 PM
Use of tRNA in Natural Product Biosynthesis
Wilfred van der Donk, Chemistry, Howard Hughes Medical Institute and University of Illinois at Urbana-Champaign, Urbana, IL
3:30 PM
Probing the mega-synthases involved in primary and secondary metabolism
Sheryl Tsai, Department of Chemistry, Department of Pharmaceutical Sciences, Department of Molecular Biology and Biochemistry, Irvine, CA
4:00 PM
Lactam-forming amide ligase found in the streptothricin biosynthetic enzymes
Yoshimitsu Hamano, Department of Bioscience, Fukui Prefectural University, Fukui, Japan
See more of: Invited Oral Papers