Monday, August 12, 2013: 1:00 PM-4:30 PM
Nautilus 3 (Sheraton San Diego)
Convener:
Sylvie Garneau-Tsodikova - University of Kentucky, Lexington, KY
1:00 PM
Piecing together the modular polyketide synthase puzzle
Adrian Keatinge-Clay1, Jianting Zheng1, Darren C. Gay1, Amanda J. Hughes1, Christopher D. Fage2, Andrew D. Harper1 and Constance B. Bailey1, (1)Chemistry and Biochemistry, The University of Texas at Austin, Austin, TX, (2)Chemistry & Biochemistry, The University of Texas at Austin, Austin, TX
Adrian Keatinge-Clay1, Jianting Zheng1, Darren C. Gay1, Amanda J. Hughes1, Christopher D. Fage2, Andrew D. Harper1 and Constance B. Bailey1, (1)Chemistry and Biochemistry, The University of Texas at Austin, Austin, TX, (2)Chemistry & Biochemistry, The University of Texas at Austin, Austin, TX
1:25 PM
Engineering acyl-CoA and carrier protein specificity of trans-acyltransferases for polyketide diversification
Gavin J. Williams1, Zhixia Ye1, Irina Koryakina1, Shan Randall1, David Muddiman1, Ewa M Musiol2 and Tilmann Weber2, (1)Department of Chemistry, North Carolina State University, Raleigh, NC, (2)Mikrobiologie/Biotechnologie, Eberhard Karls Universität Tübingen, Tübingen, Germany
Gavin J. Williams1, Zhixia Ye1, Irina Koryakina1, Shan Randall1, David Muddiman1, Ewa M Musiol2 and Tilmann Weber2, (1)Department of Chemistry, North Carolina State University, Raleigh, NC, (2)Mikrobiologie/Biotechnologie, Eberhard Karls Universität Tübingen, Tübingen, Germany
1:50 PM
Nucleoside and Peptide Antibiotics Inhibiting Bacterial Translocase I: Discovery and Chemoenzymatic Structural Modification
Steven G. Van Lanen, Pharmacy, University of Kentucky, Lexington, KY
Steven G. Van Lanen, Pharmacy, University of Kentucky, Lexington, KY
2:15 PM
Protein farnesyltransferase: A useful enzyme for the preparation of site-specific protein conjugates
Mark D. Distefano, Department of Chemisty, University of Minnesota, Minneapolis, MN
Mark D. Distefano, Department of Chemisty, University of Minnesota, Minneapolis, MN
3:10 PM
Directed discovery of unknown known natural products using molecular barcodes
Nathan A. Magarvey, Department of Biochemistry and Biomedical Sciences, The Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, ON, Canada
Nathan A. Magarvey, Department of Biochemistry and Biomedical Sciences, The Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, ON, Canada
3:35 PM
MbtH-like proteins in nonribosomal peptide biosynthesis
Sylvie Garneau-Tsodikova, Department of Pharmaceutical Sciences, University of Kentucky, Lexington, KY
Sylvie Garneau-Tsodikova, Department of Pharmaceutical Sciences, University of Kentucky, Lexington, KY
4:00 PM
Unique enzyme reaction involved in the synthesis of a carbon-nitrogen bond
Michihiko Kobayashi, Institute of Applied Biochemistry, and Graduate School of Life and Environmental Sciences, The University of Tsukuba, Tsukuba, Japan
Michihiko Kobayashi, Institute of Applied Biochemistry, and Graduate School of Life and Environmental Sciences, The University of Tsukuba, Tsukuba, Japan
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