S68: Genome mining of polyketides and nonribosomal peptides in Aspergillus nidulans

This talk will focus on the impact of whole genome sequencing on Aspergillus secondary metabolite research. There has been a proliferation of many new, intriguing discoveries since sequencing data became widely available. What is more, the genomes disclosed the surprising finding that there are many more secondary metabolite biosynthetic pathways than laboratory research had suggested. Activating these pathways by our lab and others have been met with some success, but many more dormant genes remain to be awakened.