Recruitment of bacterial genes providing resistance to bromoacetate
Kevin K. Desai and Brian G. Miller, Chemistry and Biochemistry, Florida State University, Tallahassee, FL

Unfavorable consequences of introducing a novel pathway into a pre-existing metabolic network
Shelley Copley and Juhan Kim, Molecular, Cellular and Developmental Biology, University of Colorado at Boulder, Boulder, CO

Break

Discovery and directed evolution of promiscuous enzymes
Ichiro Matsumura, Charles Daniel Murin and Andrei Ivanov, Biochemistry, Emory University, Atlanta, GA

Privileged scaffolds, "underlying" promiscuity, and convergence in the evolution of new enzyme functions
Patricia C. Babbitt, Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA

Structural insights into glutathione homeostasis
Joseph Barycki, Department of Biochemistry/Redox Biology Center, University of Nebraska, Lincoln, NE