Mixotrophic Fermentation: Methods to scale up the full potential of microalgae

Microalgae are produced using either traditional heterotrophic systems (fermenters) or more common phototrophic systems (open ponds and photobioreactors), but its trophic versatility has not yet been fully exploited. Mixotrophic microalgae can simultaneously utilize solar energy and uptake/oxidize an organic carbon source. This combined approach was first studied at small scale, but we have now developed strategies that allow large-scale cultivation.  In particular, we have studied the bacterial and algal response to acetate toxicity and designed a mixotrophic process in which acetate acts both as a substrate and a contamination controlling agent. Mixotrophy defines a new way of doing fermentation and the paper will discuss in detail the implications that this technology has in the industrial cultivation of microalgae.