Session 6: Activation of Natural Product Pathways
Wednesday, January 14, 2015: 1:30 PM-4:55 PM
California Ballroom AB
Conveners:
Kozo Ochi - Hiroshima Institute of Technology, Hiroshima, and Gilles van Wezel - Leiden University, Leiden,
Wakening of sleeping NP pathways; induction of expression using various approaches (elicitors, co-cultivation); ecological strategies; genetic regulation; metabolic engineering.


1:30 PM
S36
New strategies for drug discovery: Activation of silent or weakly expressed microbial gene clusters
Kozo Ochi, Department of Life Schience, Hiroshima Institute of Technology, Hiroshima
1:55 PM
S37
2:20 PM
S38
Chemical elicitation of secondary metabolism
Justin Nodwell and Sheila Elardo, Biochemistry, University of Toronto, Toronto, ON
2:45 PM
S39
Involvement of the 5’-UTR of afsS in the activation of actinorhodin production in Streptomyces lividans
Yasuo Ohnishi, Department of Biotechnology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo
3:10 PM
Break
3:40 PM
S40
Regulatory networks and ecological cues that control antibiotic production by actinomycetes
Gilles van Wezel1, Hua Zhu2, Chang-Sheng Wu1, Jacob Gubbens3 and Young Choi4, (1)Molecular Biotechnology, Leiden University, Leiden, The Netherlands, (2)Leiden University, Leiden, The Netherlands, (3)Department of Chemistry, Leiden University, Leiden, The Netherlands, (4)Natural Product Laboratory, Leiden University, Leiden, The Netherlands
4:05 PM
S41
Genome mining and activation of silent fungal gene clusters by microbial communication contributing to drug discovery
Axel Brakhage, Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute, Jena, Germany
4:30 PM
S42
ATP synthesis inhibitor at subinhibitory concentration
Kenji Ueda, Life Science Research Center, College of Bioresource Sciences, Nihon University, Fujisawa, Kanagawa, Japan
See more of: Invited Papers
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