Session 6:
Activation of Natural Product Pathways
Wednesday, January 14, 2015: 1:30 PM-4:55 PM
California Ballroom AB
Conveners:
Kozo Ochi - Hiroshima Institute of Technology, Hiroshima,
and
Gilles van Wezel - Leiden University, Leiden,
1:30 PM
New strategies for drug discovery: Activation of silent or weakly expressed microbial gene clusters
Kozo Ochi, Department of Life Schience, Hiroshima Institute of Technology, Hiroshima
Kozo Ochi, Department of Life Schience, Hiroshima Institute of Technology, Hiroshima
1:55 PM
Genome mining and heterologous expression for the activation of silent gene clusters in Streptomyces species
Mervyn Bibb, Molecular Microbiology, John Innes Centre, Norwich, UK
Mervyn Bibb, Molecular Microbiology, John Innes Centre, Norwich, UK
2:20 PM
Chemical elicitation of secondary metabolism
Justin Nodwell and Sheila Elardo, Biochemistry, University of Toronto, Toronto, ON
Justin Nodwell and Sheila Elardo, Biochemistry, University of Toronto, Toronto, ON
2:45 PM
Involvement of the 5’-UTR of afsS in the activation of actinorhodin production in Streptomyces lividans
Yasuo Ohnishi, Department of Biotechnology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo
Yasuo Ohnishi, Department of Biotechnology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo
3:40 PM
Regulatory networks and ecological cues that control antibiotic production by actinomycetes
Gilles van Wezel1, Hua Zhu2, Chang-Sheng Wu1, Jacob Gubbens3 and Young Choi4, (1)Molecular Biotechnology, Leiden University, Leiden, The Netherlands, (2)Leiden University, Leiden, The Netherlands, (3)Department of Chemistry, Leiden University, Leiden, The Netherlands, (4)Natural Product Laboratory, Leiden University, Leiden, The Netherlands
Gilles van Wezel1, Hua Zhu2, Chang-Sheng Wu1, Jacob Gubbens3 and Young Choi4, (1)Molecular Biotechnology, Leiden University, Leiden, The Netherlands, (2)Leiden University, Leiden, The Netherlands, (3)Department of Chemistry, Leiden University, Leiden, The Netherlands, (4)Natural Product Laboratory, Leiden University, Leiden, The Netherlands
4:05 PM
Genome mining and activation of silent fungal gene clusters by microbial communication contributing to drug discovery
Axel Brakhage, Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute, Jena, Germany
Axel Brakhage, Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute, Jena, Germany
4:30 PM
ATP synthesis inhibitor at subinhibitory concentration
Kenji Ueda, Life Science Research Center, College of Bioresource Sciences, Nihon University, Fujisawa, Kanagawa, Japan
Kenji Ueda, Life Science Research Center, College of Bioresource Sciences, Nihon University, Fujisawa, Kanagawa, Japan
See more of: Invited Papers
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