Plant pathway discovery for plant and human health

The discovery of biosynthetic pathways for plant natural products has classically been a slow process; as a consequence, few complete pathways are known. New plant genome sequences offer an opportunity to increase the rate of pathway discovery, but genomic data is not sufficient to identify the genes in a pathway that is unclustered or distributed among multiple contigs. This seminar will describe our efforts to merge transcriptomics, untargeted metabolomics, bioinformatics, and biochemistry to rapidly discover complete plant pathways for known and novel molecules, not only in the model plant Arabidopsis but also non-model plants.