Session 17
Enzyme Science and Technology III – Enzyme Discovery and Engineering
Thursday, May 1, 2014: 1:00 PM-4:25 PM
Grand Ballroom D-E, lobby level (Hilton Clearwater Beach)
Alexandre Zanghellini - Arzeda Corp., Seattle, WA and Larry E. Taylor - National Renewable Energy Laboratory, Golden, CO
Naturally occurring enzymes can be powerful tools for bioprocessing but often their characteristics can be improved. In this session will present both newly discovered enzymes and advances in enzyme engineering for improved activity, thermostability, substrate utilization, and process condition tolerance. Improvements in enzymatic lignin deconstruction and progress in reducing the cost of biomass refining enzymes will also be part of this session.

Discovery of novel cellulases from “genomic dark matter” via gene neighborhood analysis
Hailan Piao1, Jeff Froula2, Chongbin Du2, Tae-Wan Kim3, Erik Hawley2, Stefan Bauer3, Zhong Wang2, Nathalia Ivanova2, Douglas S. Clark4, Hans-Peter Klenk5 and Matthias Hess1, (1)Washington State University, Richland, WA, (2)DOE Joint Genome Institute, Walnut Creek, (3)Energy Biosciences Institute, Berkeley, CA, (4)Chemical and Biomolecular Engineering, University of California - Berkeley, Berkeley, CA, (5)Leibniz Institute-DSMZ, German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany
Enhancing cellulase commercial performance for the lignocellulosic biomass industry
Brad Kelemen1, Thijs Kaper1, Suzanne Lantz1, Edmund Larenas1, Ronald Hommes2 and Alisha Jarnagin1, (1)DuPont Industrial Biosciences, Palo Alto, CA, (2)DuPont Industrial Biosciences, Leiden, Netherlands
Metaproteogenomic approaches for target discovery of auxiliary activities that act in conjunction with glycoside hydrolases in the digestome of lower termite Coptotermes gestroi 
João Paulo L. Franco Cairo1, Macelo Falsarella Carazzolle2, Flávia Costa Leonardo2, Thabata Maria Alvarez1, Cristiane Akemi Uchima1, Thiago Augusto Gonçalves1, Ramon Oliveira Vidal2, Ana Maria Costa-Leonardo3, Fernando Ferreira Costa2, Adriana Franco Paes Leme4, Gonçalo Amarante Guimarães Pereira2 and Fabio M. Squina5, (1)Basic Research, Brazilian Bioethanol Science and Technology Laboratory, Campinas, Brazil, (2)Genetics, State University of Campinas, Campinas, Brazil, (3)Ceis, Universidade Paulista Julio de Mesquita FIlho, Rio Claro, Brazil, (4)Basic Research, Brazilian Bioscience National Laboratory, Campinas, Brazil, (5)The Brazilian Bioethanol Science and Technology Laboratory (CTBE), Campinas, Brazil
Development and adjustment of helper proteins for easier hydrolysis and adsorption
Minjeong Sohn1, Yuzhi Kang1, Bettina Bommarius1, Jay H. Lee2, Matthew J. Realff1 and Andreas S. Bommarius1, (1)School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA, (2)Dept of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, South Korea
Understanding the effects of ionic liquids on enzyme activity and stability
Michael J. Liszka1, Taya Feldman1, Joel Guenther1, Ning Sun2, Kim Tran2, Seema Singh2, Kenneth L Sale3 and Blake Simmons1, (1)Deconstruction Division, Joint BioEnergy Institute, Emeryville, CA, (2)Deconstruction Division, Joint BioEnergy Institute, Physical Biosciences Division, Lawrence Berkeley National Laboratory, Emeryville, CA, (3)Deconstruction, Joint Bioenergy Institute, Emeryville, CA
Exploring enzymatic behaviour in xylo- and phytophagous insects consortia. What could be learned from Nature ?
Claire Dumas1, Guillermina Hernandez-Raquet2, Lucile Chatellard1, Amandine Gales1, Adèle Lazuka2, Lucas Auer2, Hélène Carrère1, Jean-Jacques Godon1, Michael O'Donohue2 and Jean-Philippe Steyer1, (1)INRA UR050, Laboratoire de Biotechnologie de l'Environnement, Narbonne, France, (2)Lab d'Ingénierie des Systèmes Biologiques et des Procédés (LISBP), Institut National de la Recherche Agronomique (INRA), Toulouse, France
Production and characterization of thermophilic glycosyl- and glycoside hydrolases from Alicyclobacillus acidocaldarius
Vicki S. Thompson1, William A. Apel1, Venkatesh Balan2, Bruce Dale3 and David N. Thompson1, (1)Biological and Chemical Processing, Idaho National Laboratory, Idaho Falls, ID, (2)Department of Chemical Engineering and Materials Science,, Michigan State University and University of Pune, Lansing, MI, (3)Department of Chemical Engineering and Materials Science, Michigan State University, DOE Great Lakes Bioenergy Research Center, Lansing, MI
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