Production of ‘drop-in’ hydrocarbon fuels from plant biomass has become the target of the US Department of Energy and many other organizations.  One route to drop-in hydrocarbons is the fermentation conversion of biomass to isobutanol combined with catalytic chemistry to yield a variety of chemicals, materials and fuels.  Isobutanol from carbohydrates by fermentation has been enabled by pioneering biotechnology utilizing a novel five step pathway for the conversion of pyruvate to isobutanol.  Additionally novel recovery technology has been developed providing for low cost purification of the isobutanol.  Previously it has previously been reported that isobutanol fermentation achieved commercial performance for isobutanol titer, volumetric productivity and yield using Gevo’s integrated fermentation technology in lab scale tests.  A demonstration facility with the nominal capacity of about 1 million gallons per year was constructed and tested in collaboration with ICM in their St. Joseph, MO demonstration facility.  Preliminary engineering for the conversion of a grain ethanol facility to making isobutanol is complete and the first ethanol production site secured by Gevo will be converted to isobutanol production starting later this year.  Isobutanol is easily converted to isobutylene and a wide variety of ‘drop-in’ hydrocarbon chemicals and materials including isobutylene, para-xylene, isooctane, terephthalic acid, propylene, PET plastic, and polypropylene. The catalytic chemistry required has been previously developed and can be used to convert isobutanol to whole gasoline, jet and diesel fuels that meet all specifications for the fuels.  In this paper progress toward the commercial implementation of isobutanol production from plant carbohydrates will be presented.  Technology available for the conversion of isobutanol into whole gasoline, jet and diesel fuels will be reviewed with commercial sources for the technology identified.