Thursday, April 22, 2010 - 3:30 PM
11-05
Use of the fungus Coniochaeta ligniaria to remediate fermentation inhibitors from cellulosic sugar streams
Biochemical conversion of biomass to fuels or chemicals is often hampered by the presence of inhibitory compounds contained in sugar streams derived from lignocellulosic biomass. Dilute acid pretreatment, in particular, generates numerous fermentation inhibitors including 2-furaldehyde (furfural) and 5-hydroxymethylfurfural, along with organic acids and aromatic compounds. Inhibitory compounds must be remediated in order for efficient fermentation of biomass hydrolysates to proceed. Biological abatement is a promising approach for removing inhibitors that neither consumes chemicals nor generates wastes. In particular, fungal isolate Coniochaeta ligniaria, when inoculated into hydrolysates prior to fermentation, metabolizes inhibitory compounds, including a variety of aromatic acid, aliphatic acid, aldehyde and phenolic inhibitors. Biological abatement has been evaluated on several herbaceous sources of biomass including crop residues and potential energy crops. Bioabatement of biomass hydrolysates led to complete sugar utilization and eliminated extended fermentation lag times observed in fermentations of the unconditioned hydrolysates. Application of a bioabatement process was demonstrated in 100 liter fermentations where C. ligniaria was used to condition wheat straw hydrolysate prior to fermentation with E. coli FBR5.
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See more of The 32nd Symposium on Biotechnology for Fuels and Chemicals (April 19-22, 2010)
See more of General Submissions
See more of The 32nd Symposium on Biotechnology for Fuels and Chemicals (April 19-22, 2010)