Wednesday, May 7, 2008 - 4:30 PM
12-03

Design and Development of an Enzyme Product for Cellulosic Biomass Conversion

Aaron S. Kelley, Biomass Applications Group, Genencor, A Danisco Division, 925 Pagemill Rd., Palo Alto, CA 94304, Landon Steele, Program Management, Genencor, A Danisco Division, 925 Pagemill Rd., Palo Alto, CA 94304, and Colin Mitchinson, Genencor, A Danisco Division, 925 Page Mill Road, Palo Alto, CA 94304.

Many companies have begun process development and scale-up of their cellulosic biomass conversion technologies.  It was Genencor’s desire to quickly launch a product to support the needs of these process developers.  This paper will discuss many of the steps to launching this first commercial product specifically for this market, including the design of the enzyme system, performance testing and validation, confirming reproducible production quality and delivering on needed production cost reductions.  Performance comparisons will be shown between AccelleraseTM 1000 and SpezymeR CP, a previous benchmark cellulase product from Genencor.