General Session: Opening Remarks and Keynote Address: "Digitizing the chemical world of microbes" Pieter Dorrestein, University of California, San Diego
Sunday, August 2, 2015: 5:00 PM-6:00 PM
Freedom Ballroom, Mezzanine Level (Sheraton Philadelphia Downtown Hotel)
The chemical make-up of biology is incredibly complex. It is already difficult to analyze the molecular make up of one organism, let alone 100s or 1000s of different organisms, including the chemistry of their habitats. As mass spectrometers are becoming faster and more sensitive we can detect a lot of molecular information. There are now mass spectrometers that can analyze 10,000 samples a day. However, there is no infrastructure to analyze this amount of molecular information or to correlate this information to other Big Data generating approaches such as sequencing. On average, however, only 1-5% of all the molecular information that is collected by mass spectrometry can be annotated. It is simply too much information for one person or lab to analyze this information with the existing tools that are available. In this lecture we will explore the strategies for organizing and visualizing the massive amount of information. Topics such as molecular networking, crowd source molecular analysis, 3D topographical mapping, MS/MS rarefaction, large scale mass spectrometry based genome mining, cross correlative analysis with molecular networking and pattern based genome mining will be covered.
