Advancing Natural Product Development Using Engineering Biology

The advent of Engineering Biology has revolutionized the bio-engineering of organisms that span all Kingdoms. However, the development of full Engineering Biology platforms for non-typical organisms still lags behind that of the prototype organisms such as e.g. E. coli and yeasts for microbial chassis. In this talk, I will provide an overview of the Engineering Biology capability that Dow AgroSciences has built out and is applying to Natural Products development. I’ll highlight specific challenges and our progress in solving these. Furthermore, I will discuss how the interplay between Systems and Engineering Biology informs on the Design and Learn stages and how we are using both platforms leading to advances in our strain improvement programs for Natural Products.