Session 21: Natural Products from Eukaryotes (Fungi and Plants)
Wednesday, July 23, 2014: 8:30 AM-11:30 AM
Regency Ballroom B, Second Floor (St. Louis Hyatt Regency at the Arch)
Convener:
Jeffrey Kim - Radiant Genomics, Emeryville, CA
Recent developments in sequencing and genetic engineering have enabled the analysis and manipulation of biosynthetic pathways encoding fungal and plant-derived natural products. Insights derived from these studies suggest that diverse eukaryotic natural product biosynthetic pathways can be reconstituted in heterologous host systems, accelerating our understanding of natural product biosynthesis and enabling the large-scale production of eukaryotic natural products. This session focuses on advancements in research surrounding eukaryotic natural product biosynthesis.


8:30 AM
Technology’s Big Impact on Microbial Small-Molecule Research
Robert H. Cichewicz, Department of Chemistry and Biochemistry, Natural Products Discovery Group, Norman, OK
9:00 AM
Engineering yeast to produce artemisinic acid for anti-malarial drugs
Jessica M. Walter, Biology, Amyris, Emeryville, CA
10:00 AM
A System for Heterologous Expression of Fungal Secondary Metabolite Genes inAspergillus nidulans
Berl Oakley1, C. Elizabeth Oakley1, Clay C. C. Wang2 and Yi Ming Chiang3, (1)Department of Molecular Biosciences, University of Kansas, Lawrence, KS, (2)Pharmacology and Pharmaceutical Sciences, Univ. of Southern California, Los Angeles, CA, (3)Department of Pharmacology and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA
10:30 AM
A ten gene cluster responsible for synthesis of the anticanceralkaloid noscapine in opium poppy
Ian Graham, Centre for Novel Agricultural Products, University of York, York, United Kingdom
11:00 AM
A Carbonate-forming Baeyer-Villiger Monooxygenase in the Biosynthesis of Cytochalasin E
Youcai Hu1, Wei Xu1, Jingjing Wang1, Wen-Bing Yin1, Kangjian Qiao1, Yi Tang1 and David Dietrich2, (1)Department of Chemical and Biomolecular Engineering,, University of California Los Angeles, Los Angeles, CA, (2)Department of Chemistry, University of Alberta, Edmonton, Canada
See more of: Invited Oral Papers