Session 1: Chemo-enzymatic Approaches to Biocatalysis
Monday, July 21, 2014: 8:00 AM-11:30 AM
Regency Ballroom AB, Second Floor (St. Louis Hyatt Regency at the Arch)
Conveners:
Steven G. Van Lanen - University of Kentucky, Lexington, KY and Patrick C. Cirino - University of Houston, Houston, TX
With the advent of rapid methods towards enzyme engineering, new approaches towards metabolic engineering, and novel tools for genetic manipulation in an array of host organisms, the field of biocatalysis continues to expand. Chemoenzymatic approaches for the synthesis of complex small molecules have become important alternatives and complementary strategies to that of traditional chemical catalysts. This session will cover the spectrum from basic to applied research focusing on the development of novel enzymes/enzyme systems for the production of biofuels and medically relevant compounds.


8:00 AM
S1
Investigation and Inhibition of Siderophore Biosynthesis in Pathogenic Bacteria
Andrew M. Gulick, Department of Structural Biology, Hauptman-Woodward Medical Research Institute and University at Buffalo, Buffalo, NY
8:30 AM
S2
Mining the Microbiome for Bioactive Products
Nathan Magarvey, Department of Biochemistry and Biomedical Sciences & Chemistry and Chemical Biology, McMaster University, Hamilton, ON, Canada
9:00 AM
S3
Tools for the differential alkylation of natural products
Shanteri Singh, Jianjun Zhang, Tyler D. Huber and Jon S. Thorson, Center for Pharmaceutical Research and Innovation, College of Pharmacy,, University of Kentucky, Lexington, KY
9:30 AM
S4
10:00 AM
S5
Engineered polyketide synthases with non-natural substrate specificities
Gavin J. Williams, Chemistry, North Carolina State University, Raleigh, NC
11:00 AM
S6
The Chemoenzymatic Stature of Short Handles
Adrian Keatinge-Clay, Amanda J. Hughes, Shawn K. Piasecki, Constance B. Bailey and Darren C. Gay, Chemistry and Biochemistry, The University of Texas at Austin, Austin, TX
See more of: Invited Oral Papers