Biogas to Liquid Fuels and Chemicals Using a Methanotrophic Microorganism

Biogas derived from anaerobic digestion of waste stream sources such as MSW operations, biorefineries, and agricultural operations offers a versatile renewable energy source.  Methane-rich biogas offers a potential renewable alternative to natural gas as a feedstock in bioprocesses employing methanotrophic microorganisms. In this study, we provide proof-of-concept for a biogas-to-liquid fuels and chemicals process by genetically manipulating a methanotroph to convert methane-derived biogas to lipids and high-value co-products. Additionally, we explore the technoeconomics of such a bioprocess to demonstrate the value of this concept and determine the most economical ratio of fuel and chemical bioproduction.