Plant natural products as bacterial biofilm inhibitors
Mark O'Neil-Johnson and Gary Eldridge, Sequoia Sciences, Inc., Saint Louis, MO

Oxidative C-C deoxysugar cleavage in baumycin biosynthesis
Brian O. Bachmann¹, Hung-wen Liu² and Ahmad Al-Mestarihi¹, (1)Chemistry, Vanderbilt University, Nashville, TN, (2)College of Pharmacy, University of Texas at Austin, Austin, TX

Divergent evolution of multimodular polyketide synthases revealed through the architecture of a ketoreductase-enoylreductase didomain
Adrian Keatinge-Clay¹, Jianting Zheng¹, Darren Gay¹, Borries Demeler² and Mark A. White³, (1)Chemistry and Biochemistry, The University of Texas at Austin, Austin, TX, (2)Biochemistry, The University of Texas Health Science Center at San Antonio, San Antonio, TX, (3)Biochemistry and Molecular Biology, University of Texas Medical Branch at Galveston, Galveston, TX

Break

Chemical genetic profiling and discovery of kibdelomycin, a potent new class of bacterial type II topoisomerase inhibitor
Sheo Singh, Discovery Chemistry, Merck Research Laboratories, Rahway, NJ

Structural and functional studies of emerging polyheterocyclic antibiotics
Douglas A. Mitchell¹, Katie J. Molohon², Joel O. Melby³, Jaeheon Lee³ and Caitlin D. Deane³, (1)Chemistry and Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL, (2)Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL, (3)Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL