S118: CHOgenome.org and The International Community's Effort to Sequence the CHO K1 Genome

Tuesday, July 26, 2011: 4:00 PM
Bayside BC, 4th fl (Sheraton New Orleans)
Stephanie Hammond, Biotechnology Institute and Chemical Engineering, University of Delaware, Newark, DE
Therapeutic proteins are an important and rapidly growing segment of the pharmaceutical industry. In 2008, the annual market of biopharmaceuticals was about $90B worldwide. Today, a quarter of all FDA approved new drugs are biopharmaceuticals, most of which are produced in Chinese hamster ovary (CHO) cells. The CHO K1 cell line is an ancestor to many production cell lines. We will discuss the aspects of the genome sequence of this cell line and describe the goals of the international community's effort to share and disseminate genome-scale data from CHO cells.