Devastating effects of hurricane Katrina and of the subsequent flooding on New Orleans LA and surrounding areas are well-known.  When the flood waters receded, the submerged houses and their contents were found to be covered with molds.  Over 100 samples of water damaged organic material from homes in New Orleans, LA, were collected in October 2005 or July 2006.  The fungi obtained from these samples were identified to genus level by standard microscopic and cultural approaches.   The following genera of molds were found:  Altenaria (2 strains), Aspergillus (23 strains), Cladosporium (5 strain), Fusarium (3 strains), Penicillium (13 strains) and Trichoderma (40 strains).  To conduct a preliminary survey of volatile organic compounds (VOCs) produced by a Penicillium sp. and Trichoderma longbrachiatum, the cultures were grown on potato dextrose agar medium in a closed system and the collected VOCs were flushed out with air.  The VOCs were adsorbed on a Tenax TA resin column and analyzed by GS-MS. From this analysis more than 30 different compounds were putatively identified.   Subsequently, the same strains were grown on water-saturated dry wall in a model laboratory habitat; the samples were collected and assayed as described above.  The major VOCs detected are listed at the end.  These VOCs are being used in bioassays on Caenorhabditis elegans and Drosophila melanogaster.  Preliminary data from simple experiments indicate observable behavioral changes in wild type and mutants of both genera.