Sunday, July 26, 2009
P37
Development of an effective method for producing D-glyceric acid from raw glycerol
H. Habe1, Y. Shimada2, T. Fukuoka1, D. Kitamoto1, M. Itagaki2, K. Watanabe2, H. Yanagishita1, and K. Sakaki1. (1) Research Institute for Innovation in Sustainable Chemistry, National Institute of Advanced Industrial Science and Technology (AIST), AIST Central 5-2, 1-1-1 Higashi, Tsukuba, Ibaraki, Japan, (2) Department of Chemical Industry, Science University of Tokyo, Noda, Chiba, Japan
In the process of producing biodiesel fuel (BDF) from vegetable oils, approximately 10 wt% of glycerol is produced as a by-product. The total amount of glycerol produced worldwide is estimated to be around a million tons a year, and therefore, an effective use for this surplus glycerol has long been sought. In this study, we have developed a new technique to effectively produce D-glyceric acid from raw glycerol without its pretreatment
Although D-glyceric acid and its derivatives have excellent biological functions, including an action to accelerate alcohol metabolism, they are expensive because industrial methods have not been established for their production. If they can be produced at low cost, wide uses will be expected, including raw materials for chemical products such as bioplastics, pharmaceuticals for alcohol metabolism acceleration or liver disease treatment, and raw materials for cosmetics.
In our method for producing D-glyceric acid effectively, both an acetic acid bacterium, a highly oxidative microorganism for glycerol, was used. A Gluconobacter strain produced approximately 140 g/l GA from pure glycerol during 7 days of incubation in a jar fermentor with pH control. Also, using raw glycerol sample, approximately 80 g/l GA could be produced. This study was supported by Industrial Technology Research Grant Program in 2008 from New Energy and Industrial Technology Development Organization (NEDO) ofJapan .
Although D-glyceric acid and its derivatives have excellent biological functions, including an action to accelerate alcohol metabolism, they are expensive because industrial methods have not been established for their production. If they can be produced at low cost, wide uses will be expected, including raw materials for chemical products such as bioplastics, pharmaceuticals for alcohol metabolism acceleration or liver disease treatment, and raw materials for cosmetics.
In our method for producing D-glyceric acid effectively, both an acetic acid bacterium, a highly oxidative microorganism for glycerol, was used. A Gluconobacter strain produced approximately 140 g/l GA from pure glycerol during 7 days of incubation in a jar fermentor with pH control. Also, using raw glycerol sample, approximately 80 g/l GA could be produced. This study was supported by Industrial Technology Research Grant Program in 2008 from New Energy and Industrial Technology Development Organization (NEDO) of
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