Wednesday, July 29, 2009 - 9:00 AM
S119

DF-200: A Broad Spectrum Decontaminant for Biological Warfare Agents, Biological Pathogens, and Other Toxic Materials

Mark D. Tucker, Chemical and Biological Technologies, Sandia National Laboratories, 1515 Eubank Blvd. SE, MS0734, Albuquerque, NM 87123

Sandia National Laboratories has developed, demonstrated, and commercialized an aqueous-based decontamination formulation (DF-200) that 1) is effective for neutralizing and/or killing biological warfare agents, biological pathogens, and many other toxic materials, 2) has low toxicity and corrosivity properties, 3) can work on a number of anticipated material surfaces, and 4) can be dispersed by a variety of methods (foams, liquid sprays, fogs, and mists) that satisfy a wide variety of operational objectives.  DF-200 is considered to be one of the best available decontamination technologies by the US Department of Defense (DoD) and was staged in the Middle East as part of Operation Iraqi Freedom as well as in other locations.  Sandia has licensed the DF-200 formulation to two private companies which produce commercial products based on the technology. 

Results of tests conducted by the DoD against several strains of anthrax spores demonstrated 7-log kill of these organisms within 30 minutes.  DF-200 is also effective against many biological pathogens.  The commercial versions of DF-200 are registered with the U.S. Environmental Protection Agency against a variety of biological pathogens including the Norovirus (using Feline Calicivirus as a surrogate), MRSA, Aspergillus niger, Listeria monocytogenes, Clostridium difficile (vegetative), Penicillium variabile, Klebsiella pneumoniae, and others.  Tests have also shown DF-200 to be highly effective in the control and removal of biofilms and the neutralization of aflatoxins produced by mold. 

Sandia is a multiprogram laboratory operated by Sandia Corporation, a Lockheed Martin Company, for the United States Department of Energy under contract DE-AC04-94AL85000.


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