Thursday, August 14, 2008: 8:00 AM-11:30 AM
Golden West Room (Town and Country)
Session 29: Enzyme function and promiscuity
Convener:Shelley Copley
8:00 AMS133Hidden dimensions in protein evolution: how initially neutral variation plays a key role in the evolution of new functions
Jesse D. Bloom, Frances H. Arnold
8:30 AMS134Rational Design and Directed Evolution to Change Substrate Specificity
Jack F. Kirsch
9:00 AMS135Metabolic Expansion via Designed Enzyme Recruitment
Brian G. Miller
9:30 AM Coffee Break
10:00 AMS136Promiscuity and the evolution of enzyme functions
Margaret E. Glasner, Patricia C. Babbitt
10:30 AMS137Designing a Better Dehalogenase: Analysis of cis-3-Chloroacrylic Acid Dehalogenase and the Cg10062 Homologue
Christian P. Whitman
11:00 AMS138A compromise required by gene sharing enables survival: implications for evolution of novel enzyme activities
Shelley Copley, Sean Yu McLoughlin

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