Thursday, August 14, 2008: 8:00 AM-11:30 AM
California Room (Town and Country)
Session 31: Cell Culture and Microbial Platforms for Production of Monoclonal Antibodies and Antibody Fragments Part 1
Convener:Matthew Croughan
8:00 AMThe early stage process development experience: The "good" and the "not so good."
David Chang, Robert Bayer, Ashraf Amanullah, Judy Chou, Terry Hudson
8:30 AMEngineering of Novel Platform Cell Lines with Phenotypic Traits Advantageous for Bioproduction
Florence Wu, Paula Ravnikar, Xiaoguang Liu, Tasha Williams, Jian Liu, Gregory Vanslyke, Changlin Dou, Peggy Lio, Laurel Donahue-Hjelle
9:00 AMAntibody Production Using Mammalian Cell Culture - How High Can We Push Productivity?
Thomas Ryll
9:30 AMCoffee Break
10:00 AMDeciphering the mechanisms of therapeutic protein production iin Chinese hampster ovary (CHO) cells using systems biology approaches
Nan Lin
10:30 AMProcess economics for antibodies
Dan Abramson, Matthew Croughan
11:00 AMThe Process of Platform Evolution
Thomas Seewoester

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