Sunday, August 10, 2008
P133
Antimicrobial effects of some selected Nigerian medicinal plant extracts containing alkaloid (flavonoids) and other phenolic compounds
Chinonso Ekwueme and Edwards K. Anaga. Medical Biochemistry and INTERNAL MEDICINE, Madonna University Teaching Hospital, ELELE,, Rivers State, Nigeria
Plant phenolics, especially dietary flavonoids, are currently of growing interest owing to their supposed functional properties in promoting human health. Antimicrobial screening of 17 phenolic substances and 43 extracts prepared from Nigerian plant materials against selected microbes was conducted in this study. The tests were carried out using diffusion methods with seven to twelve microbial species (Aspergillus flavus, Aspergillus niger, Serratia marcescens , Candida albicans, Escherichia coli, Micrococcus luteus, Pseudomonas aeruginosa, Saccharomyces cerevisiae, Staphylococcus aureus ,Staphylococcus epidermidis, Streptococcus faecalis, Bacillus subtilis). Flavone, quercetin and naringenin were effective in inhibiting the growth of the organisms. Alchornea cordifolia, Annona muricata, Allium sativum.Gacinia cola and Zingiber officinale was investigated. The following fungi; Aspergillus flavus link Ex fr,Aspergillus niger Van Tieghern, Botryodiplodia theobromae (Pat) novel were inhibited by Zingiber officinale. The various bacteria were inhibited by Alchornea cordifolia, Annona muricata and Allium sativum, Adansonia digitata, Aframomum melegueta, Aloe species, Azadirachta indica, Cassia alata, Alstonia boonei, Ficus asperifolia, Cocos nucifera, Jatropha gossypyfolia, Ocimum gratissimum, Ricinus communis
Web Page: www.antimicrobials.com
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