The goal of the NABC project at Amyris is to develop the technical ability, and assess the commercial feasibility, of the fermentation of cellulosic hydrolysates to isoprenoids, especially the fermentation of xylose. Two of the major aims of the NABC project at Amyris are: 1) Engineering xylose consumption with Amyris’ isoprenoid yeast technology and 2) The evaluation of a variety of cellulosic hydrolysates on the fermentation and recovery of product.
This talk will cover Amyris’ progress towards the commercialization of biofuels from cellulosic biomass, and the engineering routes taken to attain xylose utilization in our isoprenoid yeast strains. Amyris has created isoprenoid-producing strains capable of co-consumption of glucose and xylose, and we have demonstrated isoprenoid production on cellulosic hydrolysate at 300 L scale. Amyris’ new isoprenoid manufacturing facility in Paraiso Brazil, fully operational since December 2012, would be capable of using cellulosic hydrolysate, assuming such feedstock becomes economically and commercially practical.