Harnessing the Hamster Genome Sequence for Process Enhancement in CHO Cells
Nitya M. Jacob¹, Faraaz Yusufi², Ju Xin Chin², Terk Shuen Lee², Bernard Loo², Kathryn C. Johnson¹, Ernest Retzel³, Thiru Ramaraj³, Jimmy Woodward³, John Crow³, Song Gao⁴, Niranjan Nagarajan⁴, Xiaoan Ruan⁴, Yijun Ruan⁴, Dong Yup Lee², George Karypis⁵, Miranda G.S. Yap⁶ and Wei-Shou Hu¹, (1)Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, MN, (2)Bioprocessing Technology Institute A-STAR, Singapore, Singapore, (3)National Center for Genome Resources, Santa Fe, NM, (4)Genome Institute of Singapore A-STAR, Singapore, Singapore, (5)Department of Computer Science and Engineering, University of Minnesota, Minneapolis, MN, (6)Bioprocessing Technology Institute, A*STAR, Singapore, Singapore

Genome-scale technologies for industrial bioprocess characterization: A case-study using Baby Hamster Kidney (BHK) cell cultures
Karthik P. Jayapal and Chetan T. Goudar, Cell Culture Development, Bayer HealthCare, Berkeley, CA

A Metabolic Model-based Approach to Improve Therapeutic Protein Production in Mammlian Cell Lines
Iman Famili¹, Renata Usaite¹, Adam Feist², Anne Marie Velasco¹ and Jeffrey Rosenbloom¹, (1)GT Life Sciences, Inc., San Diego, CA, (2)University of California, San Diego, La Jolla, CA

Break

HIgher Density Fed-Batch Culture through Elimination of Lactic Acid Production
Matthew Croughan¹, Nate Freund², Delyan Rusev³, Michael De La Cruz¹, Scott Cooper¹, Rahul Shah¹, Brad Davis¹ and Kirilynn Svay¹, (1)Amgen Bioprocessing Center, Keck Graduate Institute, Claremont, CA, (2)NovaVax, Inc., (3)Gilead, Inc.

Role of nutrient availability and Bcl-2Δ over-expression in controlling lactate accumulation by CHO cell cultures
Neil Templeton¹, Haimanti Dorai², Michael J. Betenbaugh³ and Jamey D. Young¹, (1)Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, (2)Centocor Biologics, Radnor, PA, (3)Dept. of Chem. and Biomolec. Engr., Johns Hopkins University, Baltimore, MD

CHOgenome.org and The International Community's Effort to Sequence the CHO K1 Genome
Stephanie Hammond, Biotechnology Institute and Chemical Engineering, University of Delaware, Newark, DE

MicroRNA regulation of apoptosis in Chinese hamster ovary cells
Alex Druz¹, Michael Betenbaugh¹, Brian Majors¹, Rodell Santuray¹, Deniz Baycin¹, Chia Chu¹ and Joseph Shiloach², (1)Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, (2)Biotechnology Core Laboratory, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Healt, Bethesda, MD